Mammograms can raise questions. SenoBright can help provide the answers.

Learn about CESM technology and how it is helping doctors make more confident decisions more quickly in breast cancer diagnosis.

Breast Imaging

Understanding breast imaging begins with understanding your breasts

Before exploring the difference SenoBright makes, let’s start with the breast basics: Your breasts have fatty tissue and dense tissue. Different women have different ratios of fatty to dense tissue in their breasts, though in general, breasts become less dense with age. Over 40% of women have dense breasts – a high proportion of dense breast tissue.1

A typical breast cancer screening begins with a standard mammogram, which may be followed up with an ultrasound if the doctor decides on the need to investigate further. Depending on different factors, such as your fat to dense tissue ratio in your breasts, the accuracy of these first line techniques may differ and results may be considered abnormal.

Following this primary workup, further testing might be needed to get a clearer picture. One such option is a SenoBright exam, which helps improve a doctor’s ability to make an accurate diagnosis. 

Learn more about:

1. Titus-Ernstoff L, Tosteson AN, Kasales C, Weiss J, Goodrich M, Hatch EE, Carney PA. Breast cancer risk factors in relation to breast density (United States) Cancer Causes Control.2006;17(10):1281–1290.

Abnormal Results

Each year in the US, 5-11% of women who undergo routine mammograms are called back in for further testing because of abnormal results.1,2

Research has shown that the anxiety a woman experiences while she waits for more testing can have long-term effects – even if the next test shows that she is cancer-free.3

SenoBright can give your doctor additional information to help shed light on your abnormal mammogram and ultrasound results, sooner.

1. Dee KE, Sickles EA. Medical audit of diagnostic mammography examinations: comparison with screening outcomes obtained concurrently. AJR Am J Roentgenol 2001;176:729–33.
2. Brown ML, Houn F, Sickles EA, Kessler LG. Screening mammography in community practice: positive predictive value of abnormal findings and yield of follow-up procedures. AJR Am J Roentgenol 1995;165:1373–7.
3. Barton MB, Morley DS, Moore S, Allen JD, Kleinman KP, Emmons KM, Fletcher SW. Decreasing women's anxieties after abnormal mammograms: a controlled trial. J Natl Cancer Institute 2004;96:529–38.

"We realize that mammography is good but there are just cases where there are questions left unanswered at the end of a mammography workup; even with ultrasound, there are just things we think we may be missing. So having another tool in our toolbox to find the information that may be hiding is great."

Dr. Bruce Schroeder, Eastern Radiologists Inc., North Carolina

Read more about how timely follow-up after an abnormal mammogram may reduce anxiety.

Mammography Imaging

A mammogram is an x-ray exam that produces a black & white picture of your breast

On a standard mammogram, the fatty tissue in your breast appears as black, while the dense tissue appears as white. Breast cancer appears also as a white spot, which can make a tumor difficult to identify when there’s dense tissue in the picture.

This difficulty can lead to inconclusive results and the doctor may prescribe an ultrasound exam for a closer look.


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Ultrasound Imaging

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An ultrasound gives a different image of your breast tissue

In an ultrasound image, also called a “sonogram”, fluid appears as black, while tissue appears as gray. The denser the tissue, the lighter gray it will appear.

A breast ultrasound is often used after abnormal mammogram results, to show whether a lump is a fluid-filled cyst or a solid mass. If the ultrasound shows a solid mass, further testing is needed to determine its cause.

CESM Imaging

Contrast-enhanced spectral mammography (CESM) can provide answers sooner

SenoBright is the first tool to use contrast-enhanced spectral mammography (CESM) technology. CESM is designed to help your doctor spot breast cancer quickly and confidently, using images that can be easily compared to the initial mammogram.

How does it work? The exam is very much like a standard mammogram. The main difference is that the exam begins with the injection of an iodine-based contrast agent, which makes any areas of increased blood supply more visible in the x-ray. Because cancer cells stimulate the development of new blood vessels, these areas may indicate that cancer is present. 

CESM then generates images of the breast using two different x-ray energy levels, and digitally combines the images. The resulting image hides dense breast tissue – the white areas – from view, and highlights any areas with increased blood supply.

The SenoBright exam takes less than 10 minutes, and the resulting image is designed to give your doctor the information needed to make a more confident diagnosis and decide whether or not you’ll need a biopsy.



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